Clenbuterol, or just “Clen”, acts on the tissues that encloses these receptors and reacts with these receptors to make different effects depending on the type of cell tissue where the receptors are in. The different adrenoreceptors in the body are labeled as Alpha or Beta followed by a number which would correspond to a certain receptor. There are nine various kinds of adrenoreceptors that can be found in the body. Its name would be written as Beta-1, Beta-2, etc. This is the same with the Alpha receptors. Each sympathomimetic and stimulant compounds act different from each other and how they affect the different receptors in the body.
Take Clenbuterol as an example. It particularly hits the Beta-2 receptors in the body which is why it is coined the Beta-2 receptor agonist. The effects of Clen to fat burning will be extensively explained in this article. The difference of its effects from steroids will also be explained as well as its anabolic properties and why it can be stacked with other anabolic steroids in the bodybuilding cycle. But the main effect of Clen is mainly to increase the metabolic activity of the body to burn fat instead of building muscle.
Not a Steroid
Although Clenbuterol can be used for burning fat, its original function has not been in this field. Sympathomimetics and stimulants are usually used as treatment for different kinds of medical conditions and these medical conditions can be treated with other different medications under this classification. One function of Clen is to treat asthma. It is the main active ingredient for a number of asthma inhalers. But today, it is not used in the US anymore because it has been replaced by Albuterol.
Clenbuterol has been found to be very effective for treating asthma because it hits the Beta-2 receptors which can be found in the cells making up the lining of the bronchial tubes. This results to a bronchial expansion in the airways in the body such as the lungs, nose and throat. In fact, all sympathomimetic compounds can be used for bronchial expansion. More than the bronchial expansion mentioned here, the human body also creates substances such as Noradrenaline and Adrenaline which also cause the same effect but to a greater extent. Other medical uses of Clenbuterol include the function as antihistamine, treatment of anaphylactic shock, allergic reactions, hypertension, migraine, arrhythmias and slowing of the cardiovascular function.
Since Clenbuterol affects the Beta-2 receptors found in the body, it also works like a Beta-2 antagonist and works together with more receptor sites although the effect is not as pronounced. An example of this is when you compare Ephedrine to Clenbuterol and you realize that Clenbuterol affects the Beta-2 receptors mostly compared to Ephedrine’s effect to both the Alpha and Beta receptors. An analogy would be when there are several nails sticking out from a piece of slab, Clenbuterol is like a hammer striking on each nail. But with Ephedrine, the effect is like hitting all the nails at the same time just like what a sledgehammer would do. This is a simple but understandable analogy of how Clenbuterol works.
Are there any anabolic, steroid-like effects?
The focus on the previous sections was on how Clenbuterol was used medically, especially as a bronchodilator. However, the main use of Clenbuterol is to aid weight loss. The anabolic effects on Clenbuterol are very minor that researchers and users alike claim that the effects are hardly even observed.
However, based on researches, there is a small chance of Clenbuterol having anabolic effects on animals such as rats but only if used for a long period of time. Therefore if you are someone planning to use Clenbuterol for anabolic effects then this product is not for you. If you take Clenbuterol especially with other supplements such as steroids, your main reason should be for weight loss and not for anabolic effects. Also, the researches that showed anabolic effects conducted on rats was on very high doses that it would be considered fata in humans therefore there is a very big chance that there is no anabolic effect brought about by Clenbuterol on humans at all.
How Clenbuterol helps lose fat and tone muscles
The main reason why Clenbuterol helps in the loss of fat is due to its effect on the Beta-2 receptors. These receptors in the fat cells become activated and therefore catalyzes the action of fat burning by breaking down triglycerides and converting them to free fatty acids. This effect is more than the effect of alpha and beta receptors in the fat cell. This effect of Clenbuterol on the metabolism is one of the main reasons why it has been administered to cattle in the past to help shed the fats and build up leaner meat.
Also you must remember that the effect of Clenbuterol can vary from person to person. Others may claim that Clenbuterol is more effective for them to lose fat while others may say that Ephedrine is more effective for them. But the most important thing to remember that although Clenbuterol has been proven to be effective to lose fat, there are people who do not have any fat burning response to this supplement at all. The recommended dosage of Clenbuterol is only once a day since its half life is estimated to be about 36 to 48 hours.
The Downregulation effect
Another important thing to tackle about Clenbuterol is that one of its effects is the downregulation of the Beta-2 receptors. When you take Clenbuterol everyday, these receptors will get used to being activated by the action of the supplement. So its efficacy and efficiency in helping lose fat will become lesser and lesser the longer you use it. There are several ways to remedy this problem. One is to stop using the supplement for 2 weeks or more. Another way is to use the antihistamine called Ketotifen Fumerate which reverses Clenbuterols downregulating effect. In the second or third week of usage, you will observe a significant decrease in its fat losing effect. This is maybe the reason why the use of Clenbuterol by bodybuilders if only for short time cycles. When you are off of Clenbuterol, you could try using other steroids too.